Simulation of Base Excision Repair in the Calculus of Covalent Bonding

Date

2018

Advisors

Journal Title

Journal ISSN

ISSN

Volume Title

Publisher

Springer

Type

Conference

Peer reviewed

Yes

Abstract

In previous papers we have introduced a new process calculus inspired by chemical reactions, called the Calculus of Covalent Bonding. The key feature of the calculus was a new prefix operator of the form (s; b), where doing of action b triggers undoing of one of the actions in s. Because of this connection between doing and undoing of actions (or forming and breaking of bonds in a chemical modelling) we called this local reversibility. We have shown that our calculus enables out-ofcausal order reversibility. In this paper we demonstrate the Base Excision Repair of DNA, a high-level biological example, using our calculus. We also introduce a software which allows us to check the syntax of processes and to simulate their execution.

Description

Keywords

Process calculi, Reversibility, Base Excision Repair, Calculus of Covalent Bonding

Citation

Kuhn, S. (2018) Simulation of Base Excision Repair in the Calculus of Covalent Bonding. In: Ulidowski, I. and Kari, J. (eds.) Reversible Computation 10th International Conference (RC 2018) proceedings, Leicester, UK, September 2018.

Rights

Research Institute