Organosulfur compounds as nutraceuticals

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dc.cclicenceN/Aen
dc.contributor.authorGoncharov, N. V.
dc.contributor.authorBELINSKAIA, D.A.
dc.contributor.authorUKOLOV, A.I.
dc.contributor.authorJenkins, R. O.
dc.contributor.authorAvdonin, P. V.
dc.date.acceptance2020
dc.date.accessioned2022-01-28T10:24:13Z
dc.date.available2022-01-28T10:24:13Z
dc.date.issued2021
dc.description.abstractOrganosulfur compounds (OSC) are widely present in our bodies and the natural environment. There are two principal groups of vegetables that contain OSC with special properties. Garlic, onion, shallot, leek, and chives are well-known representatives of the Allium genus (family Amaryllidaceae), that contain S-alk(en)yl-L-cysteine sulfoxides. Cabbage, cauliflower, Brussels sprouts, kale etc. are representatives of the Brassica genus, and rucola (rocket salad) of the Eruca genus of the mustard or cruciferous family (Brassicaceae), which contain S-methyl cysteine-L-sulfoxide. OSC as nutraceutical agents can serve not only as direct antioxidants trapping electrons, but also have non-antioxidant effects such as antiplatelet, fibrinolytic, antiinflammatory, immunomodulatory, antiageing actions etc. These properties of OSC are useful in the prophylaxis and treatment of various pathological states, such as cardiovascular diseases, cancer, neurodegenerative disorders and diabetes; they have antibacterial, antiviral and some other activities. Theories have emerged that explain these properties of OSC by their correction of redox-sensing and redox-signaling properties.en
dc.funderNo external funderen
dc.identifier.citationGONCHAROV N.V., BELINSKAIA D.A., UKOLOV A.I., JENKINS R.O. and AVDONIN P.V. (2021) Organosulfur compounds as nutraceuticals. In: Gupta RC, Lall R, Srivastava A (eds). Nutraceuticals: Efficacy, Safety and Toxicity, Second Edition. San Diego: Elsevier, pp.911-924en
dc.identifier.doihttps://doi.org/10.1016/C2019-0-02045-6
dc.identifier.isbn9780128210383
dc.identifier.isbn9780128212462
dc.identifier.urihttps://hdl.handle.net/2086/21636
dc.language.isoenen
dc.peerreviewedYesen
dc.publisherElsevieren
dc.researchinstituteInstitute for Allied Health Sciences Researchen
dc.subjectorganosulfur compoundsen
dc.subjectcystineen
dc.subjectdisulfidesen
dc.subjectsulfane sulphuren
dc.subjectgarlicen
dc.subjectonionen
dc.subjectcabbageen
dc.titleOrganosulfur compounds as nutraceuticalsen
dc.typeBook chapteren

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