The Stability of Model Human Coronaviruses on Textiles in the Environment and during Health Care Laundering

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dc.cclicenceCC-BYen
dc.contributor.authorOwen, Lucy
dc.contributor.authorShivkumar, Maitreyi
dc.contributor.authorLaird, Katie
dc.date.acceptance2021-04-07
dc.date.accessioned2021-04-29T10:50:35Z
dc.date.available2021-04-29T10:50:35Z
dc.date.issued2021-04-28
dc.descriptionopen access articleen
dc.description.abstractSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) persists on stainless steel and plastic for up to 7 days, suggesting that coronavirus disease 2019 (COVID-19) could be spread by fomite transmission. There is limited research on the stability of SARS-CoV-2 on textiles, with the risk of textiles acting as fomites not being well understood. To date, there does not appear to be any published research on the stability of coronaviruses during laundering, which is required to determine the efficacy of current laundering policies in the decontamination of health care textiles. The aim of this study was to investigate the environmental stability of human coronaviruses HCoV-OC43 and HCoV-229E on different textile fiber types and the persistence of HCoV-OC43 on textiles during domestic and industrial laundering. This study demonstrated that human coronaviruses (5 log10 50% tissue culture infective doses [TCID50]) remain infectious on polyester for ≥72 h, cotton for ≥24 h, and polycotton for ≥6 h; HCoV-OC43 was also able to transfer from polyester to PVC or polyester after 72 h. Under clean conditions, HCoV-OC43 was not detectable on cotton swatches laundered with industrial and domestic wash cycles without temperature and detergent (≥4.57-log10-TCID50 reduction), suggesting that the dilution and agitation of wash cycles are sufficient to remove human coronaviruses from textiles. In the presence of interfering substances (artificial saliva), ≤1.78 log10 TCID50 HCoV-OC43 was detected after washing domestically without temperature and detergent, unlike industrial laundering, where the virus was completely removed. However, no infectious HCoV-OC43 was detected when washed domestically with detergent.en
dc.funderOther external funder (please detail below)en
dc.funder.otherDe Montfort University HEIF Granten
dc.funder.otherTextile Services Associationen
dc.identifier.citationOwen, L., Shivkumar, M., Laird, K. (2021) The stability of model human coronaviruses on textiles in the environment and during health care laundering. mSphere, 6, e00316-21.en
dc.identifier.doihttps://doi.org/10.1128/mSphere.00316-21
dc.identifier.urihttps://dora.dmu.ac.uk/handle/2086/20811
dc.language.isoenen
dc.peerreviewedYesen
dc.projectidN/Aen
dc.publishermSphereen
dc.researchinstituteLeicester Institute for Pharmaceutical Innovation - From Molecules to Practice (LIPI)en
dc.subjectTCID50en
dc.subjectcoronavirusen
dc.subjecthealthcareen
dc.subjecthuman coronavirus OC43en
dc.subjectinfectivityen
dc.subjectlaundryen
dc.subjecttextileen
dc.titleThe Stability of Model Human Coronaviruses on Textiles in the Environment and during Health Care Launderingen
dc.typeArticleen

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