Neurofeedback of visual food cue reactivity: a potential avenue to alter incentive sensitization and craving.
| dc.cclicence | CC-BY-NC | en |
| dc.contributor.author | Ihssen, N. | en |
| dc.contributor.author | Sokunbi, Moses O. | en |
| dc.contributor.author | Lawrence, A. D. | en |
| dc.contributor.author | Lawrence, N. S. | en |
| dc.contributor.author | Linden, D. E. J. | en |
| dc.date.acceptance | 2016-05 | en |
| dc.date.accessioned | 2018-02-27T12:40:50Z | |
| dc.date.available | 2018-02-27T12:40:50Z | |
| dc.date.issued | 2016-05-27 | |
| dc.description | open access article | en |
| dc.description.abstract | FMRI-based neurofeedback transforms functional brain activation in real-time into sensory stimuli that participants can use to self-regulate brain responses, which can aid the modification of mental states and behavior. Emerging evidence supports the clinical utility of neurofeedback-guided up-regulation of hypoactive networks. In contrast, down-regulation of hyperactive neural circuits appears more difficult to achieve. There are conditions though, in which down-regulation would be clinically useful, including dysfunctional motivational states elicited by salient reward cues, such as food or drug craving. In this proof-of-concept study, 10 healthy females (mean age = 21.40 years, mean BMI = 23.53) who had fasted for 4 h underwent a novel 'motivational neurofeedback' training in which they learned to down-regulate brain activation during exposure to appetitive food pictures. FMRI feedback was given from individually determined target areas and through decreases/increases in food picture size, thus providing salient motivational consequences in terms of cue approach/avoidance. Our preliminary findings suggest that motivational neurofeedback is associated with functionally specific activation decreases in diverse cortical/subcortical regions, including key motivational areas. There was also preliminary evidence for a reduction of hunger after neurofeedback and an association between down-regulation success and the degree of hunger reduction. Decreasing neural cue responses by motivational neurofeedback may provide a useful extension of existing behavioral methods that aim to modulate cue reactivity. Our pilot findings indicate that reduction of neural cue reactivity is not achieved by top-down regulation but arises in a bottom-up manner, possibly through implicit operant shaping of target area activity. | en |
| dc.exception.reason | Published in Cardiff University repository | en |
| dc.exception.ref2021codes | 254a | en |
| dc.funder | This study was supported by the BRAINTRAIN grant, funded by the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no. 602186 and a seed corn grant of the Medical Research Council (MRC) Centre for Neuropsychiatric Genetics and Genomics, Cardiff University | en |
| dc.identifier.citation | Ihssen, N., Sokunbi, M.O., Lawrence, A.D., Lawrence, N.S. and Linden, D.E.J. (2016) Neurofeedback of visual food cue reactivity: a potential avenue to alter incentive sensitization and craving. Brain Imaging and Behavior, 11(3), pp. 915-924. | en |
| dc.identifier.doi | https://doi.org/10.1007/s11682-016-9558-x | |
| dc.identifier.issn | 1931-7557 | |
| dc.identifier.uri | http://hdl.handle.net/2086/15286 | |
| dc.language.iso | en | en |
| dc.peerreviewed | Yes | en |
| dc.projectid | 602186 | en |
| dc.publisher | Springer | en |
| dc.researchinstitute | Institute for Allied Health Sciences Research | en |
| dc.subject | Addiction | en |
| dc.subject | Brain imaging | en |
| dc.subject | Craving | en |
| dc.subject | Food pictures | en |
| dc.subject | Neurofeedback | en |
| dc.subject | Obesity | en |
| dc.subject | Visual cue reactivity | en |
| dc.subject | fMRI | en |
| dc.title | Neurofeedback of visual food cue reactivity: a potential avenue to alter incentive sensitization and craving. | en |
| dc.type | Article | en |