Application of Molecularly Imprinted Polymers in the Anti-Doping Field: Sample Purification and Compound Analysis

Date

2020-06-01

Advisors

Journal Title

Journal ISSN

ISSN

0003-2654

Volume Title

Publisher

Royal Society of Chemistry

Type

Article

Peer reviewed

Yes

Abstract

The problem posed by anti-doping requirements is one of the great analytical challenges; multiple compound detection at low ng ml−1 levels from complex samples, with requirements for exceptional confidence in results. This review surveys the design, synthesis and application of molecularly imprinted polymers (MIPs) in this field, focusing on the templating of androgenous anabolic steroids (AASs), as the most commonly abused substances, but also other WADA prohibited substances. Commentary on the application of these materials in detection, clean-up and sensing is offered, alongside views on the future of imprinting in this field.

Description

The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.

Keywords

Anti-doping, Molecular Imprinting, chromatography, WADA

Citation

Hand, R.A., Piletska, E., Bassindale, T., Morgan, G. and Turner, N. (2020) Application of molecularly imprinted polymers in the anti-doping field: sample purification and compound analysis. Analyst, 145(14), pp.4716-4736.

Rights

Research Institute