NMR and dielectric spectroscopy investigation of protein dynamical structure

Date

1990-03

Advisors

Journal Title

Journal ISSN

ISSN

Volume Title

Publisher

Elsevier

Type

Article

Peer reviewed

Yes

Abstract

The general approach to globular proteins dynamical structure investigation by NMR and time domain dielectric spectroscopy (TDDS) is presented. The information on macromolecular dynamical behavior in the case of these two methods is obtained in terms of correlation function and its parameters of atom motions. The interpretation of experimental results in the present work will be carried out in the framework of model-free approach which is common both for magnetic and dielectric relaxation. The lysozyme pH-dependence investigation is presented as an example.

Description

Keywords

Citation

Fedotov V.D. et al. (1990) NMR and dielectric spectroscopy investigation of protein dynamical structure. Journal of Molecular Structure, 219, pp. 293-298

Rights

Research Institute

Leicester Institute for Pharmaceutical Innovation - From Molecules to Practice (LIPI)