Comparison of micro- and mesoporous inorganic materials in the uptake and release of the drug model Fluorescein and its analogues.

Date

2003-12-05

Advisors

Journal Title

Journal ISSN

ISSN

1521-3765

Volume Title

Publisher

Wiley VCH

Type

Article

Peer reviewed

Abstract

Description

This paper advanced knowledge and understanding in the structure-activity relationships of zeolitic materials as a function of zeolite pore size and the nature the solvent and substrate. This work was both original and innovative and showed for the first time that compounds encapsulated within the smaller pore of a zeolite were protected from attack by enzymes in the surrounding environment, thus opening up applications in a number of industries, such as, the medical textile industry.

Keywords

RAE 2008, UoA 25 General Engineering and Mineral & Mining Engineering, UoA 13 Pharmacy

Citation

Huddersman, K., Fisher, K.A. and Taylor, M.J. (2003) Comparison of Micro- and Mesoporous Inorganic Materials in the Uptake and Release of the Drug Model Fluorescein and its Analogues. Chemistry - A European Journal, 9(23), pp. 5873-5878.

Rights

Research Institute

Leicester Institute for Pharmaceutical Innovation - From Molecules to Practice (LIPI)