Automatic Amide I frequency selection for rapid quantification of protein secondary structure from FTIR spectra of proteins

Date

2002-01-01

Authors

Innocent, P. R.
Haris, P. I. (Parvez I.)
Hering, J. A.

Advisors

Journal Title

Journal ISSN

ISSN

1615-9861
1615-9853

DOI

https://doi.org/10.1002/1615-9861(200207)2:7%3C839::aid-prot839%3E3.0.co;2-l

Volume Title

Publisher

Wiley

Type

Article

Peer reviewed

Abstract

Description

This study demonstrates how computational methods can be successfully used for automated identification of structure-sensitive regions of protein FTIR spectra. This information can then be successfully used for rapid quantification of protein secondary structure. The method developed is of interest to both academic researchers as well as pharmaceutical companies engaged in protein analysis. The impact factor of the journal is 5.735.

Keywords

RAE 2008, UoA 23 Computer Science and Informatics, Fourier transform infrared spectroscopy, genetic algorithms, neural networks, protein secondary structure prediction

Citation

Hering, J.A., Innocent, P., and Haris, P.I. (2002) Automatic Amide I frequency selection for rapid quantification of protein secondary structure from FTIR spectra of proteins. Proteomics, 2(7), pp. 839-849.

URI

http://hdl.handle.net/2086/197

Rights

Research Institute

Institute for Allied Health Sciences Research

Collections

School of Computer Science and Informatics