Screening a diverse collection of Artemisia annua germplasm accessions for the antimalarial compound, artemisinin.

Abstract

The antimalarial drug artemisinin (ART) is commercially extracted from the medicinal plant Artemisia annua L. Here, we report the screening of 70 A. annua plants representing 14 diverse germplasm accessions sourced from around the world, and identify lines containing >2% ART. These extremely high-yielding individuals have been maintained as vegetative clones, and they represent promising germplasm resources for future A. annua breeding programmes.

Description

Keywords

Malaria, Plant breeding, Chemovar, Plasmodium

Citation

Cockram J, Hill C, Burns C, Arroo RRJ, Woolley JG, Flockart I, Robinson T, Atkinson CJ, Davies MJ, Dungey N, Greenland AJ, Smith LLMJ, Bentley S (2012). Screening a diverse collection of Artemisia annua germplasm accessions for the antimalarial compound, artemisinin. Plant Genetic Resources 10 (2), pp. 152-154

Rights

Research Institute

Leicester Institute for Pharmaceutical Innovation - From Molecules to Practice (LIPI)