Role of beer as a possible protective factor in preventing Alzheimer's disease.

Date

2008-01

Advisors

Journal Title

Journal ISSN

ISSN

0278-6915

Volume Title

Publisher

Food and Chemical Toxicology

Type

Article

Peer reviewed

Yes

Abstract

Aluminium (Al), a neurotoxin, has lately been implicated as one of the possible causal factors contributing to Alzheimer's disease. Because silicon (Si) intake can affect the bioavailability of aluminium, the object of the present study was to assess whether moderate beer consumption might, as a source of dietary Si, affect the toxicokinetics of Al and thereby limit that element's neurotoxicity. The results obtained confirmed that at moderately high levels of beer intake the Si present in the beer was able to reduce Al uptake in the digestive tract and thus was able to slow the accumulation of this metal in the body, brain tissue included. In consequence, moderate beer consumption, due to its content in bioavailability silicon, possibly affording a protective factor for preventing Alzheimer's disease, could perhaps be taken into account as a component of the dietary habits of the population.

Description

Keywords

Beer, Aluminium, Silicon, Neurotoxicity

Citation

González-Muñoz, MJ., Peña, A. and Meseguer, I. (2008) Role of beer as a possible protective factor in preventing Alzheimer's disease. Food and Chemical Toxicology, 46, pp. 49-56.

Rights

Research Institute

Leicester Institute for Pharmaceutical Innovation - From Molecules to Practice (LIPI)