Anion binding to a cationic europium(iii) probe enables the first real-time assay of heparan sulfotransferase activity
Date
2021-12-08
Advisors
Journal Title
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ISSN
Volume Title
Publisher
Royal Society of Chemistry
Type
Article
Peer reviewed
Yes
Abstract
We present a new luminescent europium(iii)-based anion receptor that binds to PAP (adenosine-3′,5′-diphosphate). The increased emission intensity and lifetime of the receptor-PAP complex was used to develop the first real-time assay of heparan sulfotransferase activity.
Description
open access article
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Citation
Wheeler, S. et al. (2022) Anion binding to a cationic europium(iii) probe enables the first real-time assay of heparan sulfotransferase activity. Organic and Biomolecular Chemistry, 20, pp. 596-605