Elderberries as a potential supplement to improve vascular function in a SARS-CoV-2 environment

dc.cclicenceCC-BY-NCen
dc.contributor.authorFesta, Joseph
dc.contributor.authorSingh, Harprit
dc.contributor.authorHussain, Aamir
dc.contributor.authorDa Boit, Mariasole
dc.date.acceptance2022-01-05
dc.date.accessioned2022-02-08T11:34:15Z
dc.date.available2022-02-08T11:34:15Z
dc.date.issued2022-02-03
dc.descriptionThe Publisher's final version can be found by following the DOI link.. Open access article.en
dc.description.abstractCoronavirus disease 2019 (COVID-19) pandemic has been triggered by the severe acute respiratory syndrome coronavirus (SARS-CoV-2). Although recent studies demonstrate that SARS-CoV-2 possibly does not directly infect endothelial cells (EC), the endothelium may be affected as a secondary response due to the damage of neighboring cells, circulating pro-inflammatory cytokines, and/or other mechanisms. Long-term COVID-19 symptoms specifically nonrespiratory symptoms are due to the persistence of endothelial dysfunction (ED). Based on the literature, anthocyanins a major subgroup of flavonoid polyphenols found in berries, have been well researched for their vascular protective properties as well as the prevention of cardiovascular disease (CVD)-related deaths. Elderberries have been previously used as a natural remedy for treating influenza, cold, and consequently cardiovascular health due to a high content of cyanidin-3-glucoside (C3G) a major anthocyanin found in the human diet. The literature reported many studies demonstrating that EE has both antiviral and vascular protective properties that should be further investigated as a nutritional component used against the (in)direct effect of SARS-CoV-2 in vascular function.en
dc.funderNo external funderen
dc.identifier.citationFesta, J., Singh, H., Hussain, A. and Da Boit, M. (2022) Elderberries as a potential supplement to improve vascular function in a SARS-CoV-2 environment. Journal of Food Biochemistry, 00, e14091.en
dc.identifier.doihttps://doi.org/10.1111/jfbc.14091
dc.identifier.issn0145-8884
dc.identifier.urihttps://hdl.handle.net/2086/21676
dc.language.isoenen
dc.peerreviewedYesen
dc.publisherWileyen
dc.researchinstituteInstitute for Allied Health Sciences Researchen
dc.titleElderberries as a potential supplement to improve vascular function in a SARS-CoV-2 environmenten
dc.typeArticleen

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