Now showing items 31-40 of 64
Performance of two different microsamplers for the LC-HRMS analysis of 10 cardiovascular drugs
Introduction: Evidence suggests that ˃50% of heart disease patients do not adhere to treatment. This means half of the 370 million prescriptions dispensed for cardiovascular diseases (CVD) in the UK yearly, are wasted . ...
High resolution LC-ToF mass spectrometry data used for drug monitoring in clinical applications using dried blood spot samples
Quantitative dried blood spot (DBS) analysis was used to investigate if the accurate mass capability (±2ppm m/z) of high resolution mass spectrometry (HRMS) would provide compound specificity comparable to the multiple ...
Development of a reversed-phase HPLC method for the analysis of components from a closed-loop insulin delivery system
(Journal of Chromatography A, 2006-11-03)
Facilitating pharmacokinetic studies in children: a new use of dried blood spots.
(BMJ Publishing, 2010)
Covalent coupling of concanavalin A to a Carbopol 934P and 941P carrier in glucose-sensitive gels for delivery of insulin.
(Pharmaceutical Press, 2002-11)
Quantitative determination of atenolol in dried blood spot samples by LC-HRMS: A potential method for assessing medication adherence
The use of blood spot collection cards was investigated as a means of obtaining small volume samples for the quantification of therapeutic drugs for assessing medication adherence. A liquid chromatography-high resolution ...
Cardiovascular Drug Medication Adherence Assessed by Dried Blood Spot Analysis
(Omics Group, 2014-01)
The use of dried blood spot (DBS) collection cards was investigated for the detection of therapeutic drugs used in cardiovascular therapy for assessing medication adherence. A liquid chromatography-high resolution mass ...
It’s in a drop of blood – or is it?
Introduction: Over 355 million prescriptions were dispensed for heart diseases in the UK in 2013. Half of these, costing the NHS £2.3 billion, were wasted because patients did not take their medicines as prescribed . ...