Now showing items 1941-1950 of 1967
APC and AXIN2 Are Promising Biomarker Candidates for the Early Detection of Adenomas and Hyperplastic Polyps
Aberrant activation of the WNT/CTNNB1 pathway is notorious in colorectal cancer (CRC). Here, we demonstrate that the expression of specific and crucial WNT signaling pathway genes is linked to disease progression in colonic ...
Absorption, Distribution, Metabolism and Excretion (ADME) of Dietary Flavones and Their Glycosides
Epidemiological studies have long indicated a possible role for dietary flavonoids, notably flavones and flavonols, in the prevention of a range of degenerative diseases, e.g. cancer, diabetes, cardiovascular diseases and ...
A structured collaborative approach to intervention design using a modified intervention mapping approach: A case study using the Management and Interventions for Asthma (MIA) project for South Asian children
Background: To describe how using a combined approach of community-based participatory research and intervention mapping principles could inform the development of a tailored complex intervention to improve management of ...
Improving the quality of care in care homes using the Quality Improvement Collaborative approach: lessons learnt from six projects conducted in the UK and the Netherlands
The Breakthrough Series Quality Improvement Collaborative (QIC) initiative is a well-developed and widely used approach but most of what we know about it has come from healthcare settings. In this article, those leading ...
Thinking Outside of the Box II: Disrupting the Cognitive Map
A number of influential spatial learning theories posit that organisms encode a viewpoint independent (i.e. allocentric) representation of the global boundary shape of their environment in order to support spatial reorientation ...
The evaluation of an interactive web-based pulmonary rehabilitation programme: protocol for the Web SPACE FOR COPD feasibility study
(BMJ Open, 2015-08-25)
Introduction: Pulmonary Rehabilitation (PR) is an evidence-based intervention that has been recommended in guidelines to be available to those who may benefit. However, not all patients with chronic obstructive pulmonary ...
Perceptions of pre-exposure prophylaxis (PrEP) among HIV-negative and HIV-positive men who have sex with men.
Pre-exposure prophylaxis (PrEP) is a novel bio-medical HIV prevention op- tion for individuals at high risk of HIV exposure. This qualitative interview study ex- plores perceptions and understandings of PrEP among a sample ...