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Transcriptional response of vancomycin resistant Enterococcus faecium to a synergistic antibiotic-essential oil combination: A strategy to preserve the current antibiotic repertoire?
(2019-04)
Background: New antimicrobials to treat Vancomycin Resistant Enterococcus faecium (VRE) infections are considered a high priority. Essential oil compounds have been shown to interact synergistically with antibiotics, and ...
Cytosolic Glucosylceramide regulates endolysosomal function in Niemann-Pick type C disease
(Elsevier, 2019-03-12)
Niemann-Pick type C disease (NPCD) is a neurodegenerative disease associated with increases in cellular cholesterol and glycolipids and most commonly caused by defective NPC1, a late endosomal protein. Using ratiometric ...
Biomimetic hydroxyapatite nanocrystals are an active carrier for Salmonella bacteriophages
(International Journal of Nanomedicine - Dove Medical Press, 2019-03-28)
Purpose: The use of bacteriophages represents a valid alternative to conventional antimicrobial treatments, overcoming the widespread bacterial antibiotic resistance phenomenon. In this work, we evaluated whether biomimetic ...
Inmate-on-Staff Violence in Romanian Prisons: An Exploratory Analysis in the Context of Prisonisation Processes
(University of Bucharest and Polirom Publishing House, 2019-04-01)
The study of inmate-on-staff violence in Romanian prisons is important for both scientific and more practical reasons. For scientists, Romanian prisons and their dynamics offer an interesting case study because even though ...
Philosophy and quality? TAPUPASM as an approach to rigour in critical realist research
(RCNi, 2019-01-17)
Background
Philosophical principles should guide how research is designed, conducted and appraised. The more traditional and commonly used approaches to positivist (validity and generalisability) or interpretivist ...
Modelling the Effect of Process Parameters on the Wet Extrusion and Spheronisation of High-Loaded Nicotinamide Pellets Using a Quality by Design Approach
(MDPI, 2019-04-01)
The aim of the present study was to develop an alternative process to spray granulation in order to prepare high loaded spherical nicotinamide (NAM) pellets by wet extrusion and spheronisation. Therefore, a quality by ...
Coming 'Home": Place Bonding for parents accessing or considering hospice based care
(Health and Place, 2019-04-22)
Little literature examines the cognitive journey taken by parents considering/receiving hospice care for their child. A constructivist grounded theory study explored 38 parents’ views of considering/using a children’s ...
Integrating General Practice Nursing and Community Nursing: An Evaluation of the Rushcliffe Integrated Pilot Scheme
(De Montfort University, 2019-01-29)
Rushcliffe MCP commissioned DMU to evaluate a pilot scheme focusing on the gaps and overlaps between Community/District Nursing and General Practice Nursing. Four new nursing appointments were implemented for 12-month ...
Just another day”: The lived experience of being a hundred years old for ten New Zealanders.
(Cambridge University Press, 2019-02-19)
The aim of this study was to gain an understanding of the experiences of extended longevity
as perceived by centenarians. Centenarians (people over 100 years of age) are the
fastest growing group of the ageing population ...
The Work of the Royal College of Nursing Women’s Health Steering Group
(2019-06)
As part of the professional arm of the Royal College of Nursing, the steering group is made up of nurses who undertake roles on a voluntary basis for terms of four years.
The steering group links with other nursing ...