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    Browsing Leicester School of Pharmacy by Subject "Acute kidney injury"

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      • A Phase I study to determine the pharmacokinetic profile, safety and tolerability of sildenafil (Revatio® ) in cardiac surgery: the REVAKI-1 study. 

        Ring, Arne; Morris, Tom; Wozniak, Marcin; Sullo, N.; Dott, W.; Verheyden, Veerle; Kumar, Tracey; Brunskill, Nigel; Vaja, Rakesh; Murphy, G. J. (Article)
        AIMS: Acute kidney injury (AKI) is a common and severe complication of cardiac surgery. There is no effective prevention or treatment. Sildenafil citrate (Revatio® , Pfizer Inc.), a phosphodiesterase type 5 inhibitor, ...

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