Browsing Leicester School of Pharmacy by Subject "Acute Lung Injury"

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Bypassing adverse injection reactions to nanoparticles through shape modification and attachment to erythrocytes

Wibroe, Peter P.; Anselmo, Aaron C.; Nilsson, Per H.; Gupta, Vivek; Urbanics, Rudolf; Szebeni, Janos; Hunter, Alan Christy; Mitragotri, Samir; Mollnes, Tom Eirik; Moghimi, S. M. (Article)

Intravenously injected nanopharmaceuticals induce adverse cardiopulmonary reactions in sensitive human subjects and these reactions are reproducible in pigs. The underlying mechanisms are poorly understood, but a role for ...