Browsing Leicester School of Pharmacy by Title
Now showing items 1150-1169 of 1196
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The ultrafast dynamics of some photochromic naphthopyrans.
(Book chapter) -
Understanding sickle cell anaemia
(Article) -
Understanding the effects of a polymer on the surface dissolution of pharmaceutical cocrystals using combined experimental and molecular dynamics simulation approaches
(Article)The molecular interactions between the surfaces of cocrystals [i.e., flufenamic acid and theophylline (FFA-TP), flufenamic acid and nicotinamide (FFA-NIC), and carbamazepine and nicotinamide (CBZ-NIC)] and the polymers ... -
Undesirable and adverse effects of tooth-whitening products: a review.
(Article)Hydrogen peroxide (H2O2) is a powerful oxidising agent. It gives rise to agents known to be effective bleaching agents. The mechanisms of bleaching involve the degradation of the extracellular matrix and oxidation of ... -
Untapping the potential of terpenoid natural products as antimicrobial and anti-cancer probes
(Conference)Atractylis gummifera L. (Asteraceae) is a thistle that grows throughout the Mediterranean region and is widely known for its acute toxicity. The plant rhizome contains the active principle atractyloside (1), which consists ... -
Update on Novel Insulin Technologies
(Conference)The focus here is on the delivery of insulin by formulations that provide an alternative to subcutaneous injection and that rely mainly on gelatinous carrier materials. This will progress to the ideal of delivering an ... -
Uremic serum induced calcification of human aortic smooth muscle cells is a regulated process involving Klotho and RUNX2
(Article)Vascular calcification (VC) is common in subjects with chronic kidney disease (CKD) and is associated with increased cardiovascular risk. It is an active process involving trans-differentiation of arterial smooth muscle ... -
Urinary excretion and metabolism of miglustat and valproate in patients with Niemann-Pick Type C1 disease: one- and two-dimensional solution-state 1H NMR studies
(Article)Niemann-Pick type C1 (NP-C1) disease is a neurodegenerative lysosomal storage disease for which the only approved therapy is miglustat (MGS). In this study we explored the applications and value of both one- and two-dimensional ... -
Use of Natural Products in the Prevention and Management of Type 2 Diabetes
(Book chapter)Metabolic syndrome is an umbrella term for a group of disorders related to imbalance of energy utilization and storage. It includes obesity, hypertension, increased triglyceride levels, aberrant cholesterol levels, and ... -
The use of Quartz Crystal Microbalance as an analytical tool to monitor particles/surface and particle/particle interactions in dry ambient and pressurized conditions: a study using common inhaler components
(Article)Metered dose inhalers (MDI) and multidose powder inhalers (MPDI) are commonly used for the treatment of chronic obstructive pulmonary diseases and asthma. Currently, analytical tools to monitor particle/particle and ... -
The use of TDDS for investigation of structural and dynamic behavior of protein molecules in aqueous solution
(Article)The results of the investigation of structure and dynamic behavior of protein in solution by time-domain dielectric spectroscopy are presented. The dipole correlation functions for myoglobin, lysozyme and RNase A solutions ... -
Useful spectrokinetic methods for the investigation of photochromic and thermo-photochromic spiropyrans.
(Article)This review reports on the main results of a set of kinetic elucidation methods developed by our team over the last few years. Formalisms, procedures and examples to solve all possible AB photochromic and thermophotochromic ...