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    Browsing School of Allied Health Sciences by Subject "voltage gated potassium channel"

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      • Kv2 dysfunction after peripheral axotomy enhances sensory neuron responsiveness to sustained input. 

        Tsantoulas, Christoforos; Zhu, Lan; Yip, Ping; Grist, John; Michael, Gregory J.; McMahon, Stephen B. (Article)
        Peripheral nerve injuries caused by trauma are associated with increased sensory neuron excitability and debilitating chronic pain symptoms. Axotomy-induced alterations in the function of ion channels are ...
      • Sensory Neuron Downregulation of the Kv9.1 Potassium Channel Subunit Mediates Neuropathic Pain following Nerve Injury 

        Tsantoulas, Christoforos; Zhu, Lan; Shaifta, Yasin; Grist, John; Ward, Jeremy P. T.; Raouf, Ramin; Michael, G. J.; McMahon, Stephen B. (Article)
        Chronic neuropathic pain affects millions of individuals worldwide, is typically long-lasting, and remains poorly treated with existing therapies. Neuropathic pain arising from peripheral nerve lesions is ...

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