School of Allied Health Sciences
Recent Submissions
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Sickle Cell and Wellbeing in NHS Services
(Other)This guide is based on research examining the shielding experiences of people with sickle cell disorders (SCD) and parents of children with the condition during the COVID-19 pandemic. The aim was to improve NHS services ... -
APC and AXIN2 Are Promising Biomarker Candidates for the Early Detection of Adenomas and Hyperplastic Polyps
(Article)Aberrant activation of the WNT/CTNNB1 pathway is notorious in colorectal cancer (CRC). Here, we demonstrate that the expression of specific and crucial WNT signaling pathway genes is linked to disease progression in colonic ... -
Lipidomic UPLC-MS/MS profiles of Normal Appearing White Matter differentiate Primary and Secondary Progressive Multiple Sclerosis
(Article)Multiple sclerosis (MS) is a neurodegenerative inflammatory disease where an autoimmune response to components of the central nervous system leads to a loss of myelin and subsequent neurological deterioration. People with ... -
Development of a DNA-based microarray for the detection of zoonotic pathogens in rodent species
(Article)The demand for diagnostic tools that allow simultaneous screening of samples for multiple pathogens is increasing because they overcome the limitations of other methods, which can only screen for a single or a few pathogens ... -
Experimental modeling for delayed effects of organophosphates
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Fluoroacetate
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Russian VX
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The universal soldier: enzymatic and non-enzymatic antioxidant functions of serum albumin.
(Article)As a carrier of many biologically active compounds, blood is exposed to oxidants to a greater extent than the intracellular environment. Serum albumin plays a key role in antioxidant defence under both normal and oxidative ... -
Detection of a Yersinia pestis gene homologue in rodent samples
(Article)A homologue to a widely used genetic marker, pla, for Yersinia pestis has been identified in tissue samples of two species of rat (Rattus rattus and Rattus norvegicus) and of mice (Mus musculus and Apodemus sylvaticus) ... -
Complement Activation on Endothelial Cell-Derived Microparticles—A Key Determinant for Cardiovascular Risk in Patients with Systemic Lupus Erythematosus?
(Article)Systemic lupus erythematosus is a classical systemic autoimmune disease that overactivates complement and can affect all organs. Early diagnosis and effective management are important in this immune-complex-mediated chronic ... -
Mixing qualitative methods versus methodologies: A critical reflection on communication and power in inpatient care.
(Article)This paper offers an illustrative example to demonstrate one way of combining qualitative methods. The context for the study was a UK inpatient psychiatric hospital. Data set one was collected from weekly ward rounds where ... -
Professional sport and initial mental health public disclosure narratives
(Article)The disclosure of absences from professional sporting activities to the media is a routine and generally unproblematic part of a sporting career. However, when the reason for the absence relates to mental health concerns, ... -
Teaching interventions in a clinical degree programme to help address the UNAIDS HIV elimination targets.
(Book chapter)General awareness in chemoprophylactic preventive methods amongst undergraduate students enrolled in our two clinical science programmes at De Montfort University (DMU, Leicester, UK) was found to be very poor. To tackle ... -
Use of DMU e-Parasitology in a West African university
(Book chapter)Following the devastating effects of the 2013-16 Ebola outbreak on the Sierra Leonean public health system, De Montfort University (DMU, UK) is leading a project to build the teaching and research capabilities of medical ... -
Impact of reflective case studies on learning in clinical biochemistry.
(Book chapter)A novel pedagogic reflective strategy was developed to facilitate the teaching and learning of basic clinical biochemistry skills and to enhance critical thinking and reflection in clinical science students, specifically ... -
A structured collaborative approach to intervention design using a modified intervention mapping approach: A case study using the Management and Interventions for Asthma (MIA) project for South Asian children
(Article)Background: To describe how using a combined approach of community-based participatory research and intervention mapping principles could inform the development of a tailored complex intervention to improve management of ... -
Competing ethics in a pilot strategy to implement parasitology training and research in post-Ebola Sierra Leone.
(Article)Much of the focus of public health research post-Ebola in Sierra Leone has been on rebuilding the health care system. However, very little attention has focused on capacity building in knowledge necessary for (bio)medical ... -
Applied Barcoding: The Practicalities of DNA Testing for Herbals
(Article)DNA barcoding is a widely accepted technique for the identification of plant materials, and its application to the authentication of commercial medicinal plants has attracted significant attention. The incorporation ... -
The Discovery of Novel Antitrypanosomal 4-phenyl-6-(pyridin-3-yl)pyrimidines
(Article)Human African trypanosomiasis, or sleeping sickness, is a neglected tropical disease caused by Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense which seriously affects human health in Africa. Current therapies ...
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