Browsing by Subject "T-reg"

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Co-delivery of indoleamine 2,3-dioxygenase prevents loss of expression of an antigenic transgene in dystrophic mouse muscles.

Sharma, D.; Al-Khalidi, Rasha; Edgar, S.; An, Q.; Wang, Y.; Young, Christopher N. J.; Nowis, D.; Gorecki, Dariusz (Article)

A significant problem affecting gene therapy approaches aiming at achieving long-term transgene expression is the immune response against the protein product of the therapeutic gene, which can reduce or eliminate the ...