Browsing by Author "Taylor, M. Joan"
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Closed-loop glycaemic control using an implantable artificial pancreas in diabetic domestic pig
Taylor, M. Joan; Gregory, R.; Tomlins, P.; Jacob, D.; Hubble, J.; Sahota, T. S. (Article)The performance of a completely implantable peritoneal artificial pancreas (AP) has been demonstrated in principle in a live diabetic domestic pig. The device consists of a smart glucose-sensitive gel that forms a gateway ... -
Diffusion of fluorescent insulin from an acrylic derivatised dextran-concanavalin A gel in an implantable closed loop insulin delivery device
Jacob, D.; Taylor, M. Joan; Tomlins, P.; Sahota, T. S.; Jaroszkiewicz, E. (Conference)The drug delivery mechanism of fluorescently labelled fluorescein isothiocyanate insulin (FITC-insulin) from a glucose responsive gel held in an implantable closed loop insulin delivery device was found to be diffusion ... -
The effects of a combined aerobic and resistance exercise programme on insulin resistance among prediabetes subjects
Alharbi, Bander; Alsubaie, Nawal; Sahota, T. S.; Taylor, M. Joan (Article)Aim: Insulin resistance is a common health disorder that contributes to developed overt diabetes among prediabetes subjects. The aim of the study is to examine the effects of a combined programme of aerobic and resistance ... -
Gels for constant and smart delivery of insulin
Taylor, M. Joan; Chauhan, Krishan P; Sahota, T. S. (Article)The focus of this review is the role of gelatinous materials for oral, transdermal and peritoneal insulin platforms as alternatives to the ubiquitous subcutaneous depot approach. Hydrogels that form hydrated, cohesive ... -
Glucose lowering strategies with insulin
Taylor, M. Joan; Sahota, T. S.; Chauhan, Krishan P (Article)People with type 1 diabetes must use insulin and a large fraction of those with type 2 condition also do so. Many therefore struggle with the unpredictable balancing of insulin dose with calorie intake and utility. A healthy ...