Browsing by Author "Duffy, S Mark"

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Orai/CRACM1 and KCa3.1 ion channels interact

Duffy, S Mark; Ashmole, I.; Smallwood, Dawn T.; Leyland, Mark L.; Bradding, Peter (Article)

BACKGROUND: Orai/CRACM1 ion channels provide the major Ca(2+) influx pathway for FcεRI-dependent human lung mast cell (HLMC) mediator release. The Ca(2+)-activated K(+) channel KCa3.1 modulates Ca(2+) influx and the ...