Browsing by Author "Xiang, Y-T."

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    Cognitive functions in smoking and non-smoking patients with schizophrenia: A systematic review and meta-analysis of comparative studies
    (Elsevier, 2018-12-10) Wang, Yuan-Yuan; Wang, S.; Zheng, W.; Zhong, B-L.; Ng, C.H.; Ungvarie, G.S.; Wang, C-X.; Li, X-H.; Xiang, Y-T.
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    Meta-analysis of adherence to highly active antiretroviral therapy in patients with 55 HIV infection in China
    (Taylor and Francis, 2018-11-21) Wang, Yuan-Yuan; Jin, Y.; Chen, C.; Zheng, W.; Wang, S-B.; Ungvarie, G.S.; Ng, C.H.; Zhang, X.D.; Wang, G.; Xiang, Y-T.
    With the widespread implementation of antiretroviral therapy in many countries, the HIV/AIDS epidemic has declined. However, little is known about the prevalence of adherence rate to Highly Active Antiretroviral Therapy (HAART) in patients with HIV infection in China. We conducted the first meta-analysis of cross-sectional studies of treatment adherence ( 95%) to HAART in Chinese patients. Both English (PubMed, PsycINFO, Embase, and Web of Science) and Chinese (WanFang Database, CNKI, and SinoMed) databases were systematically and independently searched by three investigators. Studies with adherence rate estimates of HAART were included. Adherence rate estimates of each eligible study were extracted and pooled using the random-effects model. A total of 40 studies conducted in China were eligible and analyzed. The mean rate of  95% HAART adherence was 81.1% (95%CI: 75.1%- 88.0%, I2 = 97.3%) at one week, 80.9% (95%CI: 74.7%- 85.9%, I2 =96.6%) at one month, and 68.3% (95%CI: 46.1%- 84.4%, I2 = 97.1%) at 3 months or longer. Subgroup analyses revealed that samples with no gender predominance, low education level, middle economic region, rural area, older age (42.3 years or older), recent publication year (2013 or later) were correlated to higher HAART adherence. The average rate of HAART adherence was relatively high in China, which suggests effective HIV/AIDS prevention and control measures and policy. However, the level of HAART adherence tended to decrease over the treatment course.
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    Older adults at high risk of HIV infection in China: a systematic review and meta-analysis of observational studies
    (PeerJ, 2020-10-21) Wang, Yuan Yuan; Yang, Yuan; Chen, C.; Zhang, L.; Ng, C.H.; Ungvari, G.S.; Zang, X.D.; Xiang, Y-T.
    There is an increasing prevalence of human immunodeficiency virus (HIV) infection in older adults in China, but the findings across prevalence studies have been mixed. This is the first meta-analysis of the prevalence of HIV infection and its moderating factors in older adults in China. Two investigators systematically and independently earchedbothinternational(PubMed,PsycINFO,WebofSciencesandEMBASE)and Chinese (WanFang, CNKI, and CQVIP) databases. HIV infection rates in older adults wereanalyzedusingtherandom-effectsmodel.Altogether46studieswereincludedin the analysis. The pooled prevalence of HIV infection in older adults was 2.1% (95% CI[1.9%–.3%],I2=99.4%).Subgroupanalysesrevealedthatmenwhohavesexwith men(MSM),hospitalpopulationsamples,publicationsafter2014,studiesconductedin thewesternregionofChina,andhigherstudyqualityweresignificantlyassociatedwith higherHIVinfectionrate.Thismeta-analysisfoundthattheHIVinfectionprevalence in older adults is significantly higher than the general population in China. Attention should be given to this urgent public health issue, and effective HIV/AIDS preventive, screening and treatment measures are warranted in this population
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    Voluntary and involuntary admissions for severe mental illness in China: a systematic review and meta-analysis
    (American Psychiatric Association Publishing, 2019-10-02) Wang, Yuan Yuan; Yang, Yuan; Li, W.; An, F-R.; Ungvari, Gabor S.; Balbuena, L.; Xiang, Y-T.
    Aim: The aim of this systematic review and meta-analysis was to examine the prevalence of voluntary and involuntary psychiatric admissions for severe mental illness in China and explore their associated factors. Method: PubMed, Cochrane Library, PsycINFO, EMBASE, CNKI, CQVIP and WanFang databases were systematically searched. Meta-analyses were conducted using the random-effects model. Results: Fourteen studies with 94,305 patients were included. The voluntary and involuntary admission rates for all severe mental illness were 30.3% (95%CI: 18.06-46.23%), and 32.3% (95%CI: 10.39-66.21%), respectively for severe mental illness. The corresponding figures were 19.6% (95%CI: 14.09-26.54%) and 44.3% (95%CI: 5.98-90.88%), respectively for schizophrenia. Meta-regression analyses found an increase in the voluntary admission rate over time between 1998 and 2018. Conclusion: Voluntary admission rate for severe mental illness increased in China, while involuntary admission rates remained high, especially for schizophrenia. Concerted efforts are made to further decrease the rate of involuntary admissions.