Browsing by Author "Stride, E."
Now showing 1 - 9 of 9
Results Per Page
Sort Options
Item Metadata only Bioinspired bubble design for particle generation(Royal Society Publishing, 2012) Gunduz, Oguzhan; Ahmad, Z.; Stride, E.; Tamerler, Candan; Edirisinghe, M.Item Metadata only Continuous Generation of Ethyl Cellulose Drug Delivery Nanocarriers from Microbubbles(Springer, 2013) Gunduz, Oguzhan; Ahmad, Z.; Stride, E.; Edirisinghe, M.Item Metadata only A device for the fabrication of multifunctional particles from microbubble suspensions(Elsevier, 2012) Gunduz, Oguzhan; Ahmad, Z.; Stride, E.; Edirisinghe, M.Item Metadata only Electrohydrodynamic Bubbling: An Alternative Route to Fabricate Porous Structures of Silk Fibroin Based Materials(ACS Publications, 2013) Ekemen, Z.; Ahmad, Z.; Stride, E.; Kaplan, David; Edirisinghe, M.Item Metadata only Electrohydrodynamic Printing of Silk Fibroin Fiber Structures(2013) Bayram, C.; Ahmad, Z.; Denkbas, E.; Stride, E.; Edirisinghe, M.Item Metadata only Fabrication of Biomaterials via Controlled Protein Bubble Generation and Manipulation(2011-11-01) Ekemen, Z.; Chang, H.; Ahmad, Z.; Bayram, C.; Rong, Z.; Denkbas, E.; Stride, E.; Vadgama, P.; Edirisinghe, M.In this work, we utilize a recently developed microbubbling process to generate controlled protein (bovine serum albumin, BSA) coated bubbles and then manipulate these to fabricate a variety of structures suitable for several generic biomedical applications, tissue engineering, and biosensor coatings. Using BSA solutions with varying concentrations (20, 25, and 30 wt%) and cross-linking (terephthaloyl chloride) mechanisms, structures were fabricated including porous thin films with variable pore sizes and thickness (partially cross-linked coupled to bubble breakdown), scaffolds with variable pore morphologies (fully cross-linked), and coated bubbles (no cross-linking), which can be used as stand-alone delivery devices and contrast agents. The movement of typical biosensor chemicals (catechol and hydrogen peroxide) across appropriate film structures was studied. The potential of formed scaffold structures for tissue engineering applications was demonstrated using mouse cell lines (L929). In addition to low cost, providing uniform structure generation and high output, the size of the bubbles can easily be controlled by adjusting simplistic processing parameters. The combination of robust processing and chemical modification to uniform macromolecule bubbles can be utilized as a competing, yet novel, tool with current technologies and processes in advancing the biomaterials and biomedical engineering remits.Item Metadata only Generation of multi-layered structures for biomedical applications using a novel tri-needle co-axial device and electrohydrodynamic flow(2008) Ahmad, Z.; Zhang, H.; Farook, U.; Edirisinghe, M.; Stride, E.; Colombo, P.In this short communication, we describe the scope and flexibility of using a novel device containing three coaxially arranged needles to form a variety of novel morphologies. Different combinations of materials are subjected to controlled flow through the device under the influence of an applied electric field. The resulting electrohydrodynamic flow allows us to prepare doublelayered bubbles, porous encapsulated threads and nanocapsules containing three layers. The ability to process such multilayered structures is very significant for biomedical engineering applications, for example, generating capsules for drug delivery, which can provide multistage controlled release.Item Metadata only How Do Microbubbles and Ultrasound Interact? Basic Physical, Dynamic and Engineering Principles(Bentham Science Publishers, 2012) Azmin, Mehrdad; Harfield, Caroline; Ahmad, Z.; Edirisinghe, M.; Stride, E.Item Metadata only Nanoparticle delivery systems formed using electrically sprayed co-flowing excipients and active agent.(2011) Bakhshi, R.; Ahmad, Z.; Soric, M.; Stride, E.; Edirisinghe, M.