Browsing by Author "Sarker, Satyajit Dey"
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Item Metadata only Antinociceptive, anti-inflammatory, and antipyretic activity of mangrove plants: A mini review(2012) Shilpi, J. A.; Islam, M. E.; Billah, M.; Islam, K. M. D.; Sabrin, F.; Uddin, S. J.; Nahar, Lutfun; Sarker, Satyajit DeyItem Metadata only Armenin and Isoarmenin – Two Prenylated Coumarins from the aerial parts of Artemisia armeniaca.(Wiley, 2011) Mojarrab, Mahdi; Delazar, Abbas; Moghadam, Sadeighe Bamdad; Nazemiyeh, Hossein; Nahar, Lutfun; Kumarasamy, Yashodharan; Asnaashari, Solmaz; Hadjiakhoondi, Abbas; Sarker, Satyajit DeyItem Open Access Assessment of chalcones as cancer chemopreventive agents(Phytochemical Society of Europe, 2017-06-28) Jasim, Hiba; Sarker, Satyajit Dey; Moore, Sharon; Ruparelia, K. C.; Arroo, R. R. J.; Ritchie, KennethChemoprevention is based upon the use of natural or synthetic products to eliminate or minimize the development of cancer1. Many cancers are thought to occur due to processes such as oxidative stress and lipid peroxidation causing DNA damage. Chemopreventive compounds may prevent such damage from occurring. Chalcones belong to the flavonoid based group of compounds and have been reported to possess cancer chemopreventive properties2,3. In this study, we investigated the ability of novel synthetic chalcones to act as chemopreventive agents. The aim was to assess the ability of the chalcones to switch on the transcription factor Nrf2 thus inducing many cell defence genes. This was achieved using the AREc32 reporter cell line that contains the luciferase gene linked to the antioxidant response element (ARE), which is a sequence found within the promoters of cell defence genes to which the Nrf2 transcription factor binds4. The luciferase reporter AREc32 cell line was exposed to varying concentrations of synthetic chalcones to determine a suitable non-toxic concentration to use (MTT assay). The AREc32 cells were then exposed to this non-toxic concentration of chalcones for 24 h after which the amount of luciferase activity (Nrf2 activity) was quantified. Of the 30 chalcones tested, 12 chalcones were found to activate the luciferase reporter gene by 2-fold or more (relative to untreated control) with the greatest induction being 16-fold. Further investigations are now in progress to delineate the common structural features of the chalcones that give the greatest induction in addition to the ability of these chalcones to prevent cellular cytotoxicity.Item Metadata only Bioactivity of Centaurea Persica Boiss (Asteraceae)(2012) Sarker, Satyajit Dey; Nahar, Lutfun; Gujja, S.; Begum, Shazi; Celik, S.Item Metadata only Bioactivity studies on Musa seminifera Lour(MedKnow, 2013) Saha, Sanjib; Shilpi, J. A.; Mondal, Himangsu; Gofur, Royhan; Billah, M.; Nahar, Lutfun; Sarker, Satyajit DeyItem Metadata only Chemical Composition, and Antibacterial (Against Staphylococcus aureus) and Free-Radical-Scavenging Activities of the Essential Oil of Scrophularia amplexicaulis Benth.(2012) Pasdaran, A.; Delazar, Abbas; Nazemiyeh, Hossein; Nahar, Lutfun; Sarker, Satyajit DeyItem Metadata only Efficacy of Daphne oleoides subsp. kurdica used for wound healing: Identification of active compounds through bioassay guided isolation technique.(Elsevier, 2012) Suntar, I.; Küpeli Akkol, E.; Keles, H.; Yesilada, E.; Sarker, Satyajit Dey; Arroo, R. R. J.; Baykal, T.Item Metadata only Essential oil composition and isolation of free-radical-scavenging phenolic glycosides from the aerial parts of Ajuga chamaepitys growing in Iran.(2012) Delazar, Abbas; Delnavazi, M. R.; Yassa, N.; Parkhideh, S.; Delazar, N.; Nahar, Lutfun; Sarker, Satyajit DeyItem Metadata only Evaluation of anti-inflammatory activity of some Libyan medicinal plants in experimental animals(2012) Elmezogi, Jamal; Zetrini, A.; Ben-Hussein, Ghazala; Anwair, Masoud; Gbaj, Abdul; El-Ashheb, Mabrouka; Nahar, Lutfun; Sarker, Satyajit DeyItem Metadata only Follow-up of natural products isolation.(Springer, 2012) Cannell. R. J. P.; Sarker, Satyajit Dey; Nahar, LutfunItem Metadata only Hyphenated techniques and their applications in natural products analysis.(Springer, 2012) Sarker, Satyajit Dey; Nahar, LutfunItem Metadata only An introduction to natural products isolation(Springer, 2012) Sarker, Satyajit Dey; Nahar, LutfunItem Metadata only Microwave-assisted extraction in natural products isolation.(Springer, 2012) Delazar, Abbas; Nahar, Lutfun; Hamedeyazdan, S.; Sarker, Satyajit DeyItem Metadata only Phytochemistry and bioactivity of Pedicularis sibthorpii growing in Iran(SOC Brasileira Farmacognosia, 2012) Khodaie, Laleh; Delazar, Abbas; Lotfipour, F.; Nazemiyeh, Hossein; Asnaashari, Solmaz; Moghadam, Sadeighe Bamdad; Nahar, Lutfun; Sarker, Satyajit DeyItem Metadata only Supercritical fluid extraction in natural products analyses.(Springer, 2012) Nahar, Lutfun; Sarker, Satyajit DeyItem Metadata only Synthesis of 5, 6-dichloroindan-1-acids and their tetrazolyl derivatives as analgesic and anti-inflammatory agents(Bentham Science Publishers, 2012) Pal, R. K.; Yasmin, H.; Nahar, Lutfun; Datta, B. K.; Chowdhury, A. K. A.; Kundu, J. K.; Bachar, S. C.; Sarker, Satyajit DeyItem Metadata only Zanthoxylum usambarense (Engl.) Kokwaro (Rutaceae) Extracts Inhibit the Growth of the Breast Cancer Cell Lines MDA-MB-231 and MCF-7, But Not the Brain Tumour Cell Line U251 In Vitro(Wiley-Blackwell, 2013) Ozkan, M.; Mutiso, P. B. C.; Nahar, Lutfun; Liu, P.; Brown, S.; Wang, W. G.; Sarker, Satyajit Dey