Browsing by Author "Radilov, Andrey S."
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Item Metadata only Determination of fluoroacetic acid in water and biological samples by GC-FID and GC-MS in combination with solid-phase microextraction.(Springer Verlag, 2006-11-01) Jenkins, R. O.; Khlebnikova, N. S.; Koryagina, N. L.; Savelieva, E. I.; Goncharov, Nikolay V.; Radilov, Andrey S.Item Metadata only Fluroacetate(Elsevier, 2009) Goncharov, Nikolay V.; Glashkina, L.; Savelieva, E. I.; Zinchenko, V.; Teplova, V. V.; Vinokurov, M.; Kuznetsov, S.; Mindukshev, I. V.; Avdonin, P.; Jenkins, R. O.; Radilov, Andrey S.Item Metadata only Fundamental and applied research on fluoroacetate(2007-10) Goncharov, Nikolay V.; Jenkins, R. O.; Radilov, Andrey S.Item Metadata only A new method for studying platelets, based upon the low-angle light scattering technique, and its application in experimental toxicology.(2007) Mindukshev, I. V.; Goncharov, Nikolay V.; Ermolaeva, E. E.; Dobrylko, Irina A.; Senchenkova, E.; Mironova, M. O.; Jenkins, R. O.; Radilov, Andrey S.; Krivchenko. Alexander I.Item Metadata only A new method for studying platelets, based upon the low-angle light scattering technique. 3. Aggregation hypersensitivity of platelets (ADP agonist) and search for corrective agents.(ISO Press, 2006) Mindukshev, I. V.; Goncharov, Nikolay V.; Shabanova, E. Y.; Ermolaeva, E. E.; Mironova, M. O.; Radilov, Andrey S.; Jenkins, R. O.; Krivchenko. Alexander I.Item Metadata only Polarographic and spectroscopic studies of the effects of fluoroacetate/fluorocitrate on cells and mitochondria.(ISO Press, 2007) Zinchenko, V. P.; Goncharov, Nikolay V.; Teplova, V. V.; Kasymov, V. A.; Petrova, O. I.; Berezhnov, A. V.; Senchenkov, Evgeniy V.; Mindukshev, I. V.; Jenkins, R. O.; Radilov, Andrey S.Item Metadata only Russian VX(Elsevier, 2015) Rembovskiy, V.; Radilov, Andrey S.; Savelieva, E. I.; Kuznetsov, S.; Mindukshev, I. V.; Prokofieva, Daria S.; Krivorotova, N.; Khlebnikova, N. S.; Jenkins, R. O.; Goncharov, Nikolay V.Presented in this chapter are data on the principal hydrolysis products of Russian VX (RVX) with excess and equimolar quantity of water, as well as a generalized list of compounds extracted from samples of construction materials of a former RVX production facility. Toxicokinetic experiments have been conducted to determine decrease of O-alkyl methylphosphonates in blood plasma of rats after i.m. administration of RVX. MS/MS peptide spectra obtained with commercially available human albumin incubated with RVX revealed covalent binding of RVX to Tyr 411 and Tyr150. A new covalent adduct of N,N-diethyl-2-aminoethanthiol (a RVX hydrolysis product) with blood plasma proteins has been detected by HPLC–MS/MS, and this can be another marker of exposure to RVX. New data on effects developed under chronic exposure of rats to RVX are presented: these are kinetic parameters of blood platelet aggregation and electrophysiology of Nervus tibialis. According to these data, morphofunctional changes at the level of the microcirculatory bed may prove to be a significant factor in the etiology of delayed effects.Item Metadata only Russian VX: monitoring and toxicity(Elsevier, 2009) Radilov, Andrey S.; Rembovskiy, V.; Rybalchenko, I.; Savelieva, E. I.; Podolskaya, E.; Babakov, Vladimir N.; Ermolaeva, E. E.; Dulov, S.; Kuznetsov, S.; Mindukshev, I. V.; Shpak, A.; Krasnov, I.; Khlebnikova, N. S.; Jenkins, R. O.; Goncharov, Nikolay V.Item Metadata only Studies on interaction of intracellular signalling and metabolic pathways under inhibition of mitochondrial aconitase with fluoroacetate.(2007) Zinchenko, V. P.; Goncharov, Nikolay V.; Teplova, V. V.; Kasymov, V. A.; Petrova, O. I.; Berezhnov, A. V.; Senchenkov, Evgeniy V.; Mindukshev, I. V.; Jenkins, R. O.; Radilov, Andrey S.Item Metadata only Toxicology of fluoroacetate: a review, with possible directions for therapy research(John Wiley and Sons, 2005) Goncharov, Nikolay V.; Jenkins, R. O.; Radilov, Andrey S.