Browsing by Author "Chen, X. J."
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Item Metadata only Stability profiling and degradation products of dihydromyricetin in Dulbecco's modified eagle's medium.(Elsevier, 2022-01-04) Zhang, H. L.; Wang, M. L.; Yi, L. Z.; Högger, P.; Arroo, R. R. J.; Bajpai, V. K.; Prieto, M. A.; Chen, X. J.; Simal-Gandara, J.; Coa, H.Dihydromyricetin has shown many bioactivities in cell level. However, dihydromyricetin was found to be highly instable in cell culture medium DMEM. Here, the underlying degradation mechanism was investigated via UPLC-MS/MS analysis. Dihydromyricetin was mainly converted into its dimers and oxidized products. At lower temperature, dihydromyricetin in DMEM showed higher stability. Vitamin C increased the stability of dihydromyricetin in DMEM probably due to its high antioxidant potential.