Browsing by Author "Bremner, Paul"
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Item Metadata only Antifungal constituents of Melicope borbonica(John Wiley and Sons, 2004) Simonsen, H. T.; Adsersen, A.; Bremner, Paul; Heinrich, M.; Smitt, U. W.; Jaroszewski, J. W.Item Metadata only The application of a DNA-based identification technique to over-the-counter herbal medicines(Elsevier, 2013-03-13) Kazi, Tazimuddin; Hussain, Nazreen; Bremner, Paul; Slater, A.; Howard, CarolineReliable methods to identify medicinal plant material are becoming more important in an increasingly regulated market place. DNA-based methods have been recognised as a valuable tool in this area with benefits such as being unaffected by the age of the plant material, growth conditions and harvesting techniques. It is possible that the methods of production used for medicinal plant products will degrade or remove DNA. So how applicable are these techniques to processed medicinal plant products? A simple PCR-based identification technique has been developed for St. John's Wort, Hypericum perforatum L. Thirteen St. John's Wort products were purchased including capsules, tablets and tinctures.DNA was extracted from each product, and the species specific PCR test conducted. DNA was successfully extracted from all thirteen products, using a fast and efficient modified method for extracting DNA from tinctures. Only four products yielded the full length ITS region (850 bp) due to the quality of the DNA. All of the products tested positive for H. perforatum DNA. DNA-based identification methods can complement existing methods of authentication. This paper shows that these methods are applicable to a wide range of processed products, provided that they are designed to account for the possibility of DNA degradationItem Metadata only Assessing medicinal plants from South-Eastern Spain for potential anti-inflammatory effects targeting nuclear factor-Kappa B and other pro-inflammatory mediators.(Elsevier, 2009) Bremner, Paul; Rivera, D.; Calzado, M. A.; Obon, C.; Inocencio, C.; Beckwith, C.; Fiebich, B. L.; Muñoz, E.; Heinrich, M.Item Metadata only Biflavonoids with cytotoxic and antibacterial activity from Ochna macrocalyx(Georg Thieme Verlag, 2003) Tang, S.; Bremner, Paul; Kortenkamp, A.; Schlage, C.; Gray, A. I.; Gibbons, S.; Heinrich, M.Item Metadata only Calcium ionophoretic and apoptotic effects of ferutinin in the human Jurkat T-cell line(Elsevier, 2004) Macho, A.; Blanco-Molina, M.; Spagliardi, P.; Appendino, G.; Bremner, Paul; Heinrich, M.; Fiebich, B. L.; Muñoz, E.Item Metadata only Coumarins from Opopanax chironium. New dihydrofuranocoumarins and differential induction of apoptosis by imperatorin and heraclenin(American Chemical Society, 2004) Appendino, G.; Bianchi, F.; Bader, A.; Campagnuolo, C.; Fattorusso, E.; Taglialatela-Scafati, O.; Blanco-Molina, M.; Macho, A.; Fiebich, B. L.; Bremner, Paul; Heinrich, M.; Ballero, M.; Muñoz, E.Item Metadata only Cytotoxic activity of a podophyllotoxin-like lignan from Linum tauricum Willd(Veda, 2005) Vasilev, N.; Momekov, G.; Zaharieva, M.; Konstantinov, S.; Bremner, Paul; Heinrich, M.; Ionkova, I.Item Metadata only Cytotoxic versus anti-inflammatory effects in HeLa, Jurkat T and human peripheral blood cells caused by guaianolide-type sesquiterpene lactones(Elsevier, 2003) Hilmi, F.; Gertsch, J.; Bremner, Paul; Valovic, S; Heinrich, M.; Sticher, O.; Heilmann, J.Item Metadata only Ethnobotany and ethnopharmacy - Their role for anti-cancer drug development(Bentham Science Publisher Ltd., 2006) Heinrich, M.; Bremner, PaulItem Metadata only Imperatorin inhibits T-cell proliferation by targeting the transcription factor NFAT(Georg Thieme Verlag, 2004-11) Marquez, N.; Sancho, R.; Ballero, M.; Bremner, Paul; Appendino, G.; Fiebich, B. L.; Heinrich, M.; Muñoz, E.Item Metadata only The metabolic fate of dietary polyphenols in humans.(Elsevier, 2002-07-15) Bremner, Paul; Bourne, L. C.; Kuhnle, G.; Rechner, A. R.; Hubbard, Gary P.; Moore, Kevin P.; Rice-Evans, Catherine A.Item Metadata only Molecular identification of Hypericum perforatum L. by PCR amplification of the ITS and 5.8S rDNA region(Georg Thieme Verlag, 2009) Howard, Caroline; Bremner, Paul; Fowler, Mark R.; Isodo, B.; Scott, Nigel W.; Slater, A.Item Metadata only Natural products as targeted modulators of the nuclear factor-kappa B pathway(Royal Pharmecuitical Society, 2002) Bremner, Paul; Heinrich, M.Item Metadata only NF-kappa B modulators from Valeriana officinalis(John Wiley and Sons, 2006-10) Jacobo-Herrera, N. J.; Vartiainen, Nina; Bremner, Paul; Gibbons, S.; Koistinaho, J.; Heinrich, M.Item Metadata only A one-tube assay for four Hypericum species - PlantID(Georg Thieme Verlag, 2011) Howard, C.; Socratous, E.; Williams, S.; Graham, Eleanor; Fowler, Mark R.; Scott, Nigel W.; Bremner, Paul; Slater, A.Item Metadata only Phenylpropanoids NF-KB inhibitors from Bupleurum fruticosum.(Georg Thieme Verlag, 2004-09-01) Bremner, Paul; Birkmayer, H.; Fiebich, B. L.; Tang, S.; Muñoz, E.; Marquez, N.; Rivera, D.; Heinrich, M.Item Metadata only Physalins from Witheringia solanacea as modulators off the NF-kappa B cascade(American Chemical Society, 2006) Jacobo-Herrera, N. J.; Bremner, Paul; Marquez, N.; Gupta, M. P.; Gibbons, S.; Muñoz, E.; Heinrich, M.Item Metadata only PlantID - DNA-based identification of multiple medicinal plants in complex mixtures(ISCM, 2012-07-28) Howard, Caroline; Socratous, E.; Williams, S.; Graham, Eleanor; Fowler, Mark R.; Scott, Nigel W.; Bremner, Paul; Slater, A.