Effect of the Citrus Flavone Nobiletin on Circadian Rhythms and Metabolic Syndrome
| dc.cclicence | CC BY | en |
| dc.contributor.author | Neba Ambe, Gael Noel Neh | |
| dc.contributor.author | Breda, Carlo | |
| dc.contributor.author | Bhambra, Avninder S. | |
| dc.contributor.author | Arroo, R. R. J. | |
| dc.date.acceptance | 2022-11-07 | |
| dc.date.accessioned | 2022-11-10T15:22:59Z | |
| dc.date.available | 2022-11-10T15:22:59Z | |
| dc.date.issued | 2022-11-10 | |
| dc.description | Invited review paper for a special issue of Molecules on "Biological Activities of Natural Products III" (Halina Ekiert & Agnieszka Szopa, eds.) open access article | en |
| dc.description.abstract | The importance of the circadian clock in maintaining human health is now widely acknowledged. Dysregulated and dampened clocks may be a common cause of age-related diseases and metabolic syndrome Thus, circadian clocks should be considered as therapeutic targets to mitigate disease symptoms. This review highlights a number of dietary compounds that positively affect the maintenance of the circadian clock. Notably the polymethoxyflavone nobiletin has shown some encouraging results in pre-clinical experiments. Although many more experiments are needed to fully elucidate its exact mechanism of action, it is a promising candidate with potential as a chronotherapeutic agent. | en |
| dc.funder | No external funder | en |
| dc.identifier.citation | Neba Ambe GNN, Breda C, Bharmbra AS, Arroo RRJ (2022) Effect of the Citrus Flavone Nobiletin on Circadian Rhythms and Metabolic Syndrome. Molecules, 27, 7727 | en |
| dc.identifier.doi | https://doi.org/10.3390/molecules27227727 | |
| dc.identifier.uri | https://hdl.handle.net/2086/22297 | |
| dc.language.iso | en | en |
| dc.peerreviewed | Yes | en |
| dc.publisher | MDPI | en |
| dc.researchinstitute | Leicester Institute for Pharmaceutical Innovation - From Molecules to Practice (LIPI) | en |
| dc.subject | polymethoxy flavone | en |
| dc.subject | ageing | en |
| dc.subject | non-communicable diseases | en |
| dc.subject | chemoprevention | en |
| dc.title | Effect of the Citrus Flavone Nobiletin on Circadian Rhythms and Metabolic Syndrome | en |
| dc.type | Article | en |