Brain simulation as a cloud service: The Virtual Brain on EBRAINS

Files

1-s2.0-S1053811922001021-main.pdf (1.06 MB)

Date

2022-02-04

Authors

Schirner, Michael
et al.
Akintoye, Simisola
Stahl, Bernd Carsten, 1968-

Advisors

Journal Title

Journal ISSN

ISSN

1053-8119

DOI

https://doi.org/10.1016/j.neuroimage.2022.118973

Volume Title

Publisher

Elsevier

Type

Article

Peer reviewed

Yes

Abstract

The Virtual Brain (TVB) is now available as open-source services on the cloud research platform EBRAINS (ebrains.eu). It offers software for constructing, simulating and analysing brain network models including the TVB simulator; magnetic resonance imaging (MRI) processing pipelines to extract structural and functional brain networks; combined simulation of large-scale brain networks with small-scale spiking networks; automatic con- version of user-specified model equations into fast simulation code; simulation-ready brain models of patients and healthy volunteers; Bayesian parameter optimization in epilepsy patient models; data and software for mouse brain simulation; and extensive educational material. TVB cloud services facilitate reproducible online collabo- ration and discovery of data assets, models, and software embedded in scalable and secure workflows, a precondition for research on large cohort data sets, better generalizability, and clinical translation.

Description

open access article

Keywords

brain modelling, cloud, connectome, neuroimaging, network model, high performance computing, reproducibility, Data protection

Citation

Schirner, M., Domide, L., Perdikis, D., Triebkorn, P., Stefanovski, L., Pai, R., Prodan, P., Valean, B., Palmer, J., Langford, C., Blickensdörfer, A., van der Vlag, M., Diaz-Pier, S., Peyser, A., Klijn, W., Pleiter, D., Nahm, A., Schmid, O., Woodman, M., Zehl, L., Fousek, J., Petkoski, S., Kusch, L., Hashemi, M., Marinazzo, D., Mangin, J.-F., Flöel, A., Akintoye, S., Stahl, B.C., Cepic, M., Johnson, E., Deco, G., McIntosh, A.R., Hilgetag, C.C., Morgan, M., Schuller, B., Upton, A., McMurtrie, C., Dickscheid, T., Bjaalie, J.G., Amunts, K., Mersmann, J., Jirsa, V., Ritter, P. (2022) Brain simulation as a cloud service: The Virtual Brain on EBRAINS. NeuroImage, 251, 118973

URI

https://hdl.handle.net/2086/21689

Rights

Research Institute

Collections

School of Computer Science and Informatics