Role of beer as a possible protective factor in preventing Alzheimer's disease.

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dc.contributor.authorGonzalez-Munoz, M. J.en
dc.contributor.authorPena-Fernandez, A.en
dc.contributor.authorMeseguer, I.en
dc.date.accessioned2015-05-20T15:45:56Z
dc.date.available2015-05-20T15:45:56Z
dc.date.issued2008-01
dc.description.abstractAluminium (Al), a neurotoxin, has lately been implicated as one of the possible causal factors contributing to Alzheimer's disease. Because silicon (Si) intake can affect the bioavailability of aluminium, the object of the present study was to assess whether moderate beer consumption might, as a source of dietary Si, affect the toxicokinetics of Al and thereby limit that element's neurotoxicity. The results obtained confirmed that at moderately high levels of beer intake the Si present in the beer was able to reduce Al uptake in the digestive tract and thus was able to slow the accumulation of this metal in the body, brain tissue included. In consequence, moderate beer consumption, due to its content in bioavailability silicon, possibly affording a protective factor for preventing Alzheimer's disease, could perhaps be taken into account as a component of the dietary habits of the population.en
dc.funderAsociación de Cerveceros Españoles, proyect XF20 and by the project AGL-2005-07204-C02-01/ALI of the Spanish plan Nacional de Investigación Científica, Desarrollo e Innovación Tecnológica (I + D + I).en
dc.identifier.citationGonzález-Muñoz, MJ., Peña, A. and Meseguer, I. (2008) Role of beer as a possible protective factor in preventing Alzheimer's disease. Food and Chemical Toxicology, 46, pp. 49-56.en
dc.identifier.doihttps://doi.org/10.1016/j.fct.2007.06.036
dc.identifier.issn0278-6915
dc.identifier.urihttp://hdl.handle.net/2086/10968
dc.language.isoenen
dc.peerreviewedYesen
dc.projectidN/Aen
dc.publisherFood and Chemical Toxicologyen
dc.researchinstituteLeicester Institute for Pharmaceutical Innovation - From Molecules to Practice (LIPI)en
dc.subjectBeeren
dc.subjectAluminiumen
dc.subjectSiliconen
dc.subjectNeurotoxicityen
dc.titleRole of beer as a possible protective factor in preventing Alzheimer's disease.en
dc.typeArticleen

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