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Now showing items 1671-1680 of 1973
Investigation of Linum flavum (L.) Hairy Root Cultures for the Production of Anticancer Aryltetralin Lignans.
(MDPI, 2018-03-26)
Linum flavum hairy root lines were established from hypocotyl pieces using Agrobacterium rhizogenes strains LBA 9402 and ATCC 15834. Both strains were effective for transformation but induction of hairy root phenotype was ...
Flavonols with a catechol or pyrogallol substitution pattern on ring B readily form stable dimers in phosphate buffered saline at four degrees Celsius.
(Elsevier, 2019-11-14)
Phosphate buffered saline (PBS) is a buffer commonly used in biological research. The stability of a series of flavonoids, i.e. myricetin, kaempferol, baicalein, luteolin and quercetin in PBS was assessed. Apigenin proved ...
miRNAs as Regulators of Antidiabetic Effects of Fucoidans
(Atlantis Press, 2019-09-09)
Diabetes mellitus is a metabolic disease with a high mortality rate worldwide. MicroRNAs (miRNAs), and other small noncoding RNAs, serve as endogenous gene regulators through binding to specific sequences in RNA and modifying ...
Bioproduction of Anticancer Podophyllotoxin and Related Aryltretralin-Lignans in Hairy Root Cultures of Linum Flavum L.
(Springer, 2020-04-05)
Podophyllotoxin (PPT) is the unique natural precursor of Etoposide, a topoisomerase II inhibitor drug, used in more than a dozen anticancer chemotherapy treatments. Etoposide is appearing on the list of essential medicines ...
Introduction: Trauma and textualities
(Springer Nature, 2020-04-15)
This special issue of the Journal of Medical Humanities focuses on papers from an International Health Humanities Network conference held in Nottingham, UK. Informed by the centenary of World War I, the theme of ‘trauma’ ...
The impact of an intervention to increase uptake to structured self-management education for people with type 2 diabetes mellitus in primary care (the embedding package), compared to usual care, on glycaemic control: study protocol for a mixed methods study incorporating a wait-list cluster randomised controlled trial
(BMC Family Practice, 2019-11-07)
Abstract
Background
Approximately 425 million people globally have diabetes, with ~ 90% of these having Type 2 Diabetes Mellitus (T2DM). This is a condition that leads to a poor quality of life and increased risk of ...
Application of normalisation process theory in understanding implementation processes in primary care settings in the UK: a systematic review
(BMC Family Practice, 2020-03-16)
Abstract Background: Normalisation Process Theory (NPT) provides a framework to understand how interventions are implemented, embedded, and integrated in healthcare settings. Previous reviews of published literature have ...
Flavones as tyrosinase inhibitors: kinetic studies in vitro and in silico.
(Wiley, 2020-01-29)
Introduction – Tyrosinase is a multifunctional copper-containing oxidase enzyme that catalyzes the first steps in the formation of melanin pigments. Identification of tyrosinase inhibitors is of value for applications in ...
A workshop on Dietary Sweetness—Is It an Issue?
(Springer Nature, 2018-03-13)
This report summarises a workshop convened by ILSI Europe on 3 and 4 April 2017 to discuss the issue of dietary sweetness. The objectives were to understand the roles of sweetness in the diet, establish whether exposure ...
I Can't Go Back Because If I Go Back I Would Die: How Asylum Seekers Manage Talk about Returning Home by Highlighting the Importance of Safety
(Wiley, 2014-11-08)
Asylum seekers living in the UK have been shown to have fled danger in their countries of origin, only to face hardship and the threat of deportation once there. This paper draws on the discursive psychological approach ...
