Now showing items 1-10 of 13
HIV Progression to AIDS: Bioinformatics Approach to Determining the Mechanism of Action
(Bentham Science Publishers, 2013-01)
The mechanism by which HIV infection transforms into AIDS disease is unclear. Several factors such as the decline in immune response, increase in replication rate, Syncytium inducing capacity and ability of the viruses to ...
Signal-processing-based bioinformatics approach for the identification of influenza A virus subtypes in Neuraminidase genes.
Neuraminidase (NA) genes of influenza A virus is a highly potential candidate for antiviral drug development that can only be realized through true identification of its sub-types. In this paper, in order to accurately ...
A framework towards computational discovery of disease sub-types and associated (sub-)biomarkers.
Biomarker related patient data is generally assessed in order to determine relevant but generalized subset of the biomarkers. However, it fails to identify specific sub-groups of the patients or their corresponding (subset ...
Construction of protein distance matrix based on amino acid indices and Discrete Fourier Transform.
Protein distance matrix is widely used in various protein sequence analyses, and mainly obtained by using pairwise sequence alignment scores or protein sequence homology, which fail to take into consideration of individual ...