Browsing by Subject "C1q"

Now showing items 1-1 of 1

Structural basis of the C1q/C1s interaction and its central role in assembly of the C1 complex of complement activation

Venkatraman Girija, U.; Gingras, A. R.; Marshall, J. E.; Panchal, R.; Sheikh, M. A.; Gal, P.; Schwaeble, W. J.; Mitchell, D. A.; Moody, P. C.; Wallis, R. (Article)

Complement component C1, the complex that initiates the classical pathway of complement activation, is a 790-kDa assembly formed from the target-recognition subcomponent C1q and the modular proteases C1r and C1s. The ...