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    Browsing by Author "Di Miceli, Mathieu"

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      • Chronic methylphenidate treatment during adolescence has long-term effects on monoaminergic function. 

        Di Miceli, Mathieu; Omoloye, Adesina; Gronier, Ben (Article)
        Background: Psychostimulants like methylphenidate or D-amphetamine are often prescribed for attention deficit and hyperactivity disorders in children. Whether such drugs can be administered into a developing brain without ...
      • The impact of psychostimulant administration during development on adult brain functions controlling motivation, impulsivity and cognition. 

        Di Miceli, Mathieu (Thesis)
        ADHD pharmacotherapy uses methylphenidate (MPH), D-amphetamine (D-amph), two psychostimulants targeting dopamine transporters, or atomoxetine (ATX), specifically targeting norepinephrine transporters. We have assessed the ...
      • The impact of psychostimulant administration during development on adult brain functions controlling motivation, impulsivity and cognition. 

        Di Miceli, Mathieu (Thesis or dissertation / Doctoral / PhD)
        ADHD pharmacotherapy uses methylphenidate (MPH), D-amphetamine (D- amph), two psychostimulants targeting dopamine transporters, or atomoxetine (ATX), specifically targeting norepinephrine transporters. We have assessed the ...
      • In silico Hierarchical Clustering of Neuronal Populations in the Rat Ventral Tegmental Area Based on Extracellular Electrophysiological Properties 

        Di Miceli, Mathieu; Husson, Zoe; Ruel, Philippe; Laye, Sophie; Cota, Daniela; Fioramonti, Xavier; Bosh-Bouju, Clementine; Gronier, Ben (Article)
        The ventral tegmental area (VTA) is a heterogeneous brain region, containing different neuronal populations. During in vivo recordings, electrophysiological characteristics are classically used to distinguish the different ...
      • Increased cortical neuronal responses to NMDA and improved attentional set-shifting performance in rats following prebiotic (B-GOS®) ingestion. 

        Gronier, Ben; Savignac, H. M.; Di Miceli, Mathieu; Idris, S. M.; Tzortzis, G.; Anthony, D.; Burnet, P.W.J. (Article)
        We have previously shown that prebiotics (dietary fibres that augment the growth of indigenous beneficial gut bacteria) such as Bimuno™ galacto-oligosaccharides (B-GOS®), increased N-methyl-D-aspartate (NMDA) receptor ...
      • Pharmacology, Systematic Review and Recent Clinical Trials of Metadoxine 

        Di Miceli, Mathieu; Gronier, Ben (Article)
        Abstract: Background: Metadoxine is composed of pyroglutamic acid and vitamin B6. Administrations of metadoxine are indicated in cases of acute alcohol intoxication or in chronic alcoholism. Objectives: To reference ...
      • Psychostimulants and atomoxetine alter the electrophysiological activity of prefrontal cortex neurons, interaction with catecholamine and glutamate NMDA receptors. 

        Di Miceli, Mathieu; Gronier, Ben (Article)
        RATIONALE: Attention-deficit hyperactivity disorder (ADHD) is the most frequently diagnosed neuropsychiatric disorder in childhood. Currently available ADHD drugs include the psychostimulants methylphenidate (MPH) and ...

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