Browsing by Author "Abhishek, P."

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    Effect of meta-cognitive training in the reduction of positive symptoms in schizophrenia
    (Taylor and Francis, 2010-08-03) Dubey, Indu; Kumar, D.; Haq, M.Z.U.; Dotiwala, K.N.; Siddiqui, S.V.; Prakash, R.; Abhishek, P.; Nizamie, S.H.
    Metacognitive training (MCT), a variant of Cognitive Behaviour Therapy, is a recently developed therapeutic method that targets active positive symptoms, primarily delusions. It translates basic research related to cognitive biases behind these symptoms into a training procedure for schizophrenia patients. To see the effectiveness of MCT a total of sixteen recently admitted schizophrenia patients were randomly divided into two groups. One group underwent treatment as usual (TAU) and the other group underwent MCT plus TAU. The MCT group showed steeper decline in positive symptoms with medium to large effect sizes. Findings are discussed in the light of their practical implications.
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    Long-term Vihangam Yoga meditation and scores on tests of attention
    (Perceptual and Motor Skills, 2010-06-01) Dubey, Indu; Prakash, R.; Abhishek, P.; Gupta, S.K.; Rastogi, P.; Siddiqui, S.V.
    Although the literature indicates that meditation has beneficial effects on several aspects of human functioning, few studies have specifically investigated the effects of meditation on various domains of attention. This study was conducted to examine the differences in various domains of attention between long-term concentrative meditators versus matched controls. 15 practitioners of Vihangam Yoga (> 10 yr. experience) were enrolled in the study. Controls matched on age, sex, and years of education were recruited. Both groups were administered the Stroop, Trail-Making, and Digit Symbol Substitution tests as well as the Digit Forward and Digit Backward tests. The group of Vihangam Yogis had significantly better mean performance on all tests of attention. Long-term Vihangam Yoga meditation improves attention span, processing speed, attention alternation ability, and performance in interference tests.
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    Lower P300 amplitudes for internally-generated events in patients with schizophrenia
    (Elsevier, 2018-06) Dubey, Indu; Abhishek, P.; Nizamie, S.H.; Goyal, N.; Tikka, S.K.; Pachori, H.; Kumar, D.; Katshu, M.Z.U.H.
    BACKGROUND: Patients with schizophrenia demonstrate difficulty differentiating internally-generated from externally-generated events. An excessive deployment of attention to external events as well as poor processing of self-generated events has been proposed to explain this misattribution. This study was done to understand the neurophysiological basis of source monitoring bias in schizophrenia. METHODS: Seventeen patients and fourteen healthy controls completed a two-stage source monitoring task involving solving a three-letter jumbled word either by the participant or a computer following which they had to identify the correct source of the word - solved by self (internal source monitoring, ISM) or by computer (external source monitoring, ESM) - while EEG was recorded. P300 amplitude and latency were computed separately for ISM and ESM conditions. RESULTS: P300 amplitude for ISM condition was lower in patients with schizophrenia compared to controls over right and left parietal regions. Additionally, P300 amplitude for ISM condition was lower compared to ESM condition in patients over right and left parietal regions. However, P300 amplitude for ESM condition did not differ significantly between the groups. In contrast to P300 amplitude, there was no significant difference in P300 latency in ISM or ESM condition within or between the groups. CONCLUSION: P300 amplitude was lower for internally-generated but not externally-generated events in patients with schizophrenia. These findings suggest that patients allocate less attentional resources to internally generated events resulting in poorer processing and consequent misattribution of their source of origin. This study provides the first specific electrophysiological evidence of impaired source monitoring in schizophrenia.